Illusion of Evidence-Based Medicine: Examining the Scientific Foundation of Clinical Research

Jureidini, Jon
Illusion of Evidence-Based Medicine: Examining the Scientific Foundation of Clinical Research

Illusion of Evidence-Based Medicine: Examining the Scientific Foundation of Clinical Research

Jureidini, Jon

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An exposé of two highly influential trials, closely tied to the pharmaceutical industry, that affected how we treat paediatric and adolescent depression.

In a transpacific collaboration based on ten years of research, two university researchers from Australia and California, Jon N. Jureidini and Leemon B. McHenry, expose the scientific misconduct of two infamous studies. Both of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline’s paroxetine study 329 and Forest Laboratories citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.

The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine.

Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.

Author:   Jureidini, Jon
Publisher:   Wakefield Press
ISBN:  

9781743057247


Publication Date:   01 September 2020
Availability:  
This item is in stock and will be dispatched immediately.

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An exposé of two highly influential trials, closely tied to the pharmaceutical industry, that affected how we treat paediatric and adolescent depression.

In a transpacific collaboration based on ten years of research, two university researchers from Australia and California, Jon N. Jureidini and Leemon B. McHenry, expose the scientific misconduct of two infamous studies. Both of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline’s paroxetine study 329 and Forest Laboratories citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.

The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine.

Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.

Product Details
Author:   Jureidini, Jon
Publisher:   Wakefield Press
ISBN:  

9781743057247


Publication Date:   01 September 2020
Availability:  
This item is in stock and will be dispatched immediately.
Reviews

Reviews

Recent Reviews

No review item found!